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WellRank™

Zinc ranks 61 of 169 Osteoporosis treatments based on 7 research articles we have analyzed from 221 relevant articles we identified. The relationship is in the bottom 5% of our analyses.

Safety

There have been 33,385 reported side effects for Zinc in the US. The 5 most reported: Nausea, Dyspnoea, Anosmia, Diarrhoea, Ageusia.

Safety

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What researchers say about Zinc as Osteoporosis Treatment

Researchers report:

  • Based on the available experimental and clinical evidence, we update our earlier proposal that [Zinc] deficiency plays a role in the pathogenesis of senile [Osteoporosis]....However, the mechanism of [Zinc] deficiency in [Osteoporosis] remains unclear....Therefore, [Zinc] replacement by dietary [Zinc] supplementation might be valuable to prevent or treat senile [Osteoporosis]....Additional studies are necessary for the evaluation of the possible role of [Zinc] in the etiology of senile [Osteoporosis].1
  • A relationship has also been established between metacarpal index of [Osteoporosis] and plasma [Zinc] concentrations in rheumatoid subjects.2
  • Having observed previously that the reduction of levels of biological markers of nutrition in [Osteoporosis] may be related to [Zinc] deficiency, we measured plasma and urinary [Zinc] concentrations in 30 women with [Osteoporosis] and in 30 healthy postmenopausal women who served as controls....Plasma [Zinc] levels did not differ between groups, but urinary [Zinc] excretion was significantly higher in the women with [Osteoporosis] (p = 0....Likewise, the relation between TBBMC/W and plasma and urinary [Zinc] levels also was significant in the women with [Osteoporosis] but not in the controls (multiple regression analysis: p = 0....TBBMC correlated with urinary [Zinc] concentration significantly in the women with [Osteoporosis] (simple linear regression: r = 0....These findings indicate that the elevation of urinary [Zinc] elimination in [Osteoporosis] is dependent on bone resorption.3
  • The relation of [Zinc] to the aging skeleton was investigated in 140 women aged 36-85 years, mostly postmenopausal, who attended the Jerusalem [Osteoporosis] Center.4
  • Until recently these observational data were supported by the findings of an intervention study that showed a protective role for vitamin K(1) (together with calcium, magnesium, [Zinc], and vitamin D(3)) on [Osteoporosis] over 3 years in early postmenopausal women.5

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About Zinc

Zinc, in commerce also spelter, is a chemical element with symbol Zn and atomic number 30. It is the first element of group 12 of the periodic table. In some respects zinc is chemically similar to magnesium: its ion is of similar size and its only common oxidation state is +2. Zinc is the 24th most abundant element in Earth's crust and has five stable isotopes. The most common zinc ore is sphalerite (zinc blende), a zinc sulfide mineral. The largest mineable amounts are found in Australia, Asia, and the United States. Zinc production includes froth flotation of the ore, roasting, and final extraction using electricity (electrowinning).1

About Osteoporosis

Osteoporosis ("porous bones", from Greek: οστούν/ostoun meaning "bone" and πόρος/poros meaning "pore") is a progressive bone disease that is characterized by a decrease in bone mass and density which can lead to an increased risk of fracture. In osteoporosis, the bone mineral density (BMD) is reduced, bone microarchitecture deteriorates, and the amount and variety of proteins in bone are altered. Osteoporosis is defined by the World Health Organization (WHO) as a bone mineral density of 2.5 standard deviations or more below the mean peak bone mass (average of young, healthy adults) as measured by dual-energy X-ray absorptiometry; the term "established osteoporosis" includes the presence of a fragility fracture. The disease may be classified as primary type 1, primary type 2, or secondary. The form of osteoporosis most common in women after menopause is referred to as primary type 1 or postmenopausal osteoporosis, which is attributable to the decrease in estrogen production after menopause. Primary type 2 osteoporosis or senile osteoporosis occurs after age 75 and is seen in both females and males at a ratio of 2:1. Secondary osteoporosis may arise at any age and affect men and women equally; this form results from chronic predisposing medical problems or disease, or prolonged use of medications such as glucocorticoids, when the disease is called steroid- or glucocorticoid-induced osteoporosis.2

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Research last analyzed February 19, 2015 @11:15PM.

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