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37% Complete

The relationship between Glutathione and Peripheral neuropathy is somewhat weak. Glutathione ranks 65 of 803 Peripheral neuropathy treatments we have analyzed.

Peripheral neuropathy (PN) is damage or disease affecting nerves, which may impair sensation, movement, gland or organ function, or other aspects of health, depending on the type of nerve affected. Common causes include systemic diseases (such as diabetes or leprosy), vitamin deficiency, medication (e.g., chemotherapy), traumatic injury, excessive alcohol consumption, immune system disease, or infection, or it may be inherited (present from birth). In conventional medical usage, the word neuropathy (neuro-, "nervous system" and -pathy, "disease of") without modifier usually means peripheral neuropathy.1

Glutathione (GSH) is an important antioxidant in plants, animals, fungi and some bacteria and archaea, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. It is a tripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side-chain and the amine group of cysteine (which is attached by normal peptide linkage to a glycine).2

Researchers have concluded:

  • Releasing ROS to injure mitochondrion and endoplasmic reticulum maybe involved in bortezomib induced peripheral neuropathy. Although reduced glutathione can inhibit ROS release, it has no obviously reversal effect for peripheral neuropathy.3

Review all research »

Strength of evidence

Glutathione for Peripheral neuropathy ranks in the bottom 37% of condition-treatment relationships we analyzed.

Importantly, we found only 1 studies that were randomized and controlled. Such studies are considered the most rigorous, and help to establish or disprove a cause-and-effect relationship between prospective treatments and conditions. So there may be some good evidence on which to make a decision about using Glutathione for Peripheral neuropathy.

Amount of research

The relationship between Peripheral neuropathy and Glutathione has been modestly researched. We found 134 research articles on the topic. This places the volume of research in the bottom 37% of condition-treatment relationships we have analyzed.

Research trends

Are researchers becoming more or less interested in Glutathione for Peripheral neuropathy? The pace of research appears to be increasing.

Important caveat—help improve this information

Please note that our analysis is automated and imperfect. If you have personal insight, please help improve our analysis by rating this relationship and the research supporting it. And check back regularly; we last analyzed research for this relationship on July 27, 2014 @12:09AM, and are constantly updating our database and algorithms.


Other names
Glutathione for Peripheral neuropathy is also known as C10H17N3O6S for Neuropathy, C10H17N3O6S for Peripheral Neuropathies, C10H17N3O6S for Peripheral sensory neuropathy, C10H17N3O6S for Neuritis, C10H17N3O6S for Mononeuropathy, C10H17N3O6S for Mononeuropathies, C10H17N3O6S for Neuropathic, C10H17N3O6S for Neuropathies, C10H17N3O6S for Neuropathic eye pain, C10H17N3O6S for Mononeuritis multiplex, C10H17N3O6S for Peripheral autonomic neuropathy, C10H17N3O6S for Sensory neuropathy, C10H17N3O6S for Peripheral nervous system diseases, C10H17N3O6S for Polyneuritis, C10H17N3O6S for Arsenic neuritis, C10H17N3O6S for Sensory neuropathy type 1, C10H17N3O6S for Disorders of peripheral nervous system, C10H17N3O6S for Autoimmune peripheral neuropathy, C10H17N3O6S for Radiculoneuropathy, C10H17N3O6S for Gram-positive bacterial infection, C10H17N3O6S for Gram-negative bacterial infection, C10H17N3O6S for Peripheral neuritis, C10H17N3O6S for Mononeuritis, C10H17N3O6S for Motor neuropathy, C10H17N3O6S for Generalized peripheral neuropathy, C10H17N3O6S for Mononeuritic multiplex, C10H17N3O6S for Peripheral Neuropathy, C10H17N3O6S for Hereditary peripheral nervous disorder, C10H17N3O6S for Peripheral nervous disorder, C10H17N3O6S for Deafferentation, C10H17N3O6S for Mononeuropathy multiplex, Copren for Neuropathy, Copren for Peripheral Neuropathies, Copren for Peripheral sensory neuropathy, Copren for Neuritis, Copren for Mononeuropathy, Copren for Mononeuropathies, Copren for Neuropathic, Copren for Neuropathies, Copren for Neuropathic eye pain, Copren for Mononeuritis multiplex, Copren for Peripheral autonomic neuropathy, Copren for Sensory neuropathy, Copren for Peripheral nervous system diseases, Copren for Polyneuritis, Copren for Arsenic neuritis, Copren for Sensory neuropathy type 1, Copren for Disorders of peripheral nervous system, Copren for Autoimmune peripheral neuropathy, Copren for Radiculoneuropathy, Copren for Gram-positive bacterial infection, Copren for Gram-negative bacterial infection, Copren for Peripheral neuritis, Copren for Mononeuritis, Copren for Motor neuropathy, Copren for Generalized peripheral neuropathy, Copren for Mononeuritic multiplex, Copren for Peripheral Neuropathy, Copren for Hereditary peripheral nervous disorder, Copren for Peripheral nervous disorder, Copren for Deafferentation, Copren for Mononeuropathy multiplex, Glutathion for Neuropathy, Glutathion for Peripheral Neuropathies, Glutathion for Peripheral sensory neuropathy, Glutathion for Neuritis, Glutathion for Mononeuropathy, Glutathion for Mononeuropathies, Glutathion for Neuropathic, Glutathion for Neuropathies, Glutathion for Neuropathic eye pain, Glutathion for Mononeuritis multiplex, Glutathion for Peripheral autonomic neuropathy, Glutathion for Sensory neuropathy, Glutathion for Peripheral nervous system diseases, Glutathion for Polyneuritis, Glutathion for Arsenic neuritis, Glutathion for Sensory neuropathy type 1, Glutathion for Disorders of peripheral nervous system, Glutathion for Autoimmune peripheral neuropathy, Glutathion for Radiculoneuropathy, Glutathion for Gram-positive bacterial infection, Glutathion for Gram-negative bacterial infection, Glutathion for Peripheral neuritis, Glutathion for Mononeuritis, Glutathion for Motor neuropathy, Glutathion for Generalized peripheral neuropathy, Glutathion for Mononeuritic multiplex, Glutathion for Peripheral Neuropathy, Glutathion for Hereditary peripheral nervous disorder, Glutathion for Peripheral nervous disorder, Glutathion for Deafferentation, Glutathion for Mononeuropathy multiplex, Glutathione metabolism for Neuropathy, Glutathione metabolism for Peripheral Neuropathies, Glutathione metabolism for Peripheral sensory neuropathy, Glutathione metabolism for Neuritis, Glutathione metabolism for Mononeuropathy, Glutathione metabolism for Mononeuropathies, Glutathione metabolism for Neuropathic, Glutathione metabolism for Neuropathies, Glutathione metabolism for Neuropathic eye pain, 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Top treatments for Peripheral neuropathy

Insulin
94% Complete
Bortezomib
93% Complete
Paclitaxel
93% Complete
Cisplatin
91% Complete
Oxaliplatin
90% Complete
Gabapentin
89% Complete
Pregabalin
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Dexamethasone
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Fluorouracil
83% Complete
Albumin
82% Complete