11% Complete

The relationship between Vitamin B12 and Migraine is weak. Vitamin B12 ranks 160 of 614 Migraine treatments we have analyzed.

Migraine is a chronic neurological disorder characterized by recurrent moderate to severe headaches often in association with a number of autonomic nervous system symptoms. The word derives from the Greek ἡμικρανία (hemikrania), "pain on one side of the head", from ἡμι- (hemi-), "half", and κρανίον (kranion), "skull".1

Methylcobalamin (shown) is a form of Vitamin B12. Physically it resembles the other forms of vitamin B12, occurring as dark red crystals that freely form cherry-colored transparent solutions in water. Vitamin B12, vitamin B12 or vitamin B-12, also called cobalamin, is a water-soluble vitamin with a key role in the normal functioning of the brain and nervous system, and for the formation of blood. It is one of the eight B vitamins. It is normally involved in the metabolism of every cell of the human body, especially affecting DNA synthesis and regulation, but also fatty acid metabolism and amino acid metabolism. Neither fungi, plants, nor animals are capable of producing vitamin B12. Only bacteria and archaea have the enzymes required for its synthesis, although many foods are a natural source of B12 because of bacterial symbiosis. The vitamin is the largest and most structurally complicated vitamin and can be produced industrially only through bacterial fermentation-synthesis.2

Strength of evidence

Vitamin B12 for Migraine ranks in the bottom 11% of condition-treatment relationships we analyzed.

Importantly, we found only 1 studies that were randomized and controlled. Such studies are considered the most rigorous, and help to establish or disprove a cause-and-effect relationship between prospective treatments and conditions. So there may be some good evidence on which to make a decision about using Vitamin B12 for Migraine.

Amount of research

The relationship between Migraine and Vitamin B12 has been modestly researched. We found 13 research articles on the topic. This places the volume of research in the bottom 30% of condition-treatment relationships we have analyzed.

Research trends

Are researchers becoming more or less interested in Vitamin B12 for Migraine? The pace of research appears to be decreasing.

Important caveat—help improve this information

Please note that our analysis is automated and imperfect. If you have personal insight, please help improve our analysis by rating this relationship and the research supporting it. And check back regularly; we last analyzed research for this relationship on July 26, 2014 @9:49AM, and are constantly updating our database and algorithms.

Other names
Vitamin B12 for Migraine is also known as B12 with dermatosis for Amigrainous migraine, B12 with dermatosis for Anti-migraine, B12 with dermatosis for Basilar artery migraines, B12 with dermatosis for Basilar migraine, B12 with dermatosis for Basilar type migraine, B12 with dermatosis for Bickerstaff's migraine, B12 with dermatosis for Classical migraine, B12 with dermatosis for Common migraine, B12 with dermatosis for Facial migraine, B12 with dermatosis for Megrims, B12 with dermatosis for Migraine disorders, B12 with dermatosis for Migraine headache, B12 with dermatosis for Migraine headaches, B12 with dermatosis for Migraine journal, B12 with dermatosis for Migraine medication, B12 with dermatosis for Migraines, B12 with dermatosis for Migrane, B12 with dermatosis for Mígren, B12 with dermatosis for Mígreni, B12 with dermatosis for Optical migraine, Behepan for Amigrainous migraine, Behepan for Anti-migraine, Behepan for Basilar artery migraines, Behepan for Basilar migraine, Behepan for Basilar type migraine, Behepan for Bickerstaff's migraine, Behepan for Classical migraine, Behepan for Common migraine, Behepan for Facial migraine, Behepan for Megrims, Behepan for Migraine disorders, Behepan for Migraine headache, Behepan for Migraine headaches, Behepan for Migraine journal, Behepan for Migraine medication, Behepan for Migraines, Behepan for Migrane, Behepan for Mígren, Behepan for Mígreni, Behepan for Optical migraine, Cobalamine for Amigrainous migraine, Cobalamine for Anti-migraine, Cobalamine for Basilar artery migraines, Cobalamine for Basilar migraine, Cobalamine for Basilar type migraine, Cobalamine for Bickerstaff's migraine, Cobalamine for Classical migraine, Cobalamine for Common migraine, Cobalamine for Facial migraine, Cobalamine for Megrims, Cobalamine for Migraine disorders, Cobalamine for Migraine headache, Cobalamine for Migraine headaches, Cobalamine for Migraine journal, Cobalamine for Migraine medication, Cobalamine for Migraines, Cobalamine for Migrane, Cobalamine for Mígren, Cobalamine for Mígreni, Cobalamine for Optical migraine, Colbalamin for Amigrainous migraine, Colbalamin for Anti-migraine, Colbalamin for Basilar artery migraines, Colbalamin for Basilar migraine, Colbalamin for Basilar type migraine, Colbalamin for Bickerstaff's migraine, Colbalamin for Classical migraine, Colbalamin for Common migraine, Colbalamin for Facial migraine, Colbalamin for Megrims, Colbalamin for Migraine disorders, Colbalamin for Migraine headache, Colbalamin for Migraine headaches, Colbalamin for Migraine journal, Colbalamin for Migraine medication, Colbalamin for Migraines, Colbalamin for Migrane, Colbalamin for Mígren, Colbalamin for Mígreni, Colbalamin for Optical migraine, Vitamin b 12 for Amigrainous migraine, Vitamin b 12 for Anti-migraine, Vitamin b 12 for Basilar artery migraines, Vitamin b 12 for Basilar migraine, Vitamin b 12 for Basilar type migraine, Vitamin b 12 for Bickerstaff's migraine, Vitamin b 12 for Classical migraine, Vitamin b 12 for Common migraine, Vitamin b 12 for Facial migraine, Vitamin b 12 for Megrims, Vitamin b 12 for Migraine disorders, Vitamin b 12 for Migraine headache, Vitamin b 12 for Migraine headaches, Vitamin b 12 for Migraine journal, Vitamin b 12 for Migraine medication, Vitamin b 12 for Migraines, Vitamin b 12 for Migrane, Vitamin b 12 for Mígren, Vitamin b 12 for Mígreni, Vitamin b 12 for Optical migraine, Vitamin B-12 for Amigrainous migraine, Vitamin B-12 for Anti-migraine, Vitamin B-12 for Basilar artery migraines, Vitamin B-12 for Basilar migraine, Vitamin B-12 for Basilar type migraine, Vitamin B-12 for Bickerstaff's migraine, Vitamin B-12 for Classical migraine, Vitamin B-12 for Common migraine, Vitamin B-12 for Facial migraine, Vitamin B-12 for Megrims, Vitamin B-12 for Migraine disorders, Vitamin B-12 for Migraine headache, Vitamin B-12 for Migraine headaches, Vitamin B-12 for Migraine journal, Vitamin B-12 for Migraine medication, Vitamin B-12 for Migraines, Vitamin B-12 for Migrane, Vitamin B-12 for Mígren, Vitamin B-12 for Mígreni, Vitamin B-12 for Optical migraine, Vitamin b12 for Amigrainous migraine, Vitamin b12 for Anti-migraine, Vitamin b12 for Basilar artery migraines, Vitamin b12 for Basilar migraine, Vitamin b12 for Basilar type migraine, Vitamin b12 for Bickerstaff's migraine, Vitamin b12 for Classical migraine, Vitamin b12 for Common migraine, Vitamin b12 for Facial migraine, Vitamin b12 for Megrims, Vitamin b12 for Migraine disorders, Vitamin b12 for Migraine headache, Vitamin b12 for Migraine headaches, Vitamin b12 for Migraine journal, Vitamin b12 for Migraine medication, Vitamin b12 for Migraines, Vitamin b12 for Migrane, Vitamin b12 for Mígren, Vitamin b12 for Mígreni, Vitamin b12 for Optical migraine, B12 with dermatosis for Migraine, Behepan for Migraine, Cobalamine for Migraine, Colbalamin for Migraine, Vitamin b 12 for Migraine, Vitamin B-12 for Migraine, Vitamin b12 for Migraine, Vitamin B12 for Amigrainous migraine, Vitamin B12 for Anti-migraine, Vitamin B12 for Basilar artery migraines, Vitamin B12 for Basilar migraine, Vitamin B12 for Basilar type migraine, Vitamin B12 for Bickerstaff's migraine, Vitamin B12 for Classical migraine, Vitamin B12 for Common migraine, Vitamin B12 for Facial migraine, Vitamin B12 for Megrims, Vitamin B12 for Migraine disorders, Vitamin B12 for Migraine headache, Vitamin B12 for Migraine headaches, Vitamin B12 for Migraine journal, Vitamin B12 for Migraine medication, Vitamin B12 for Migraines, Vitamin B12 for Migrane, Vitamin B12 for Mígren, Vitamin B12 for Mígreni and Vitamin B12 for Optical migraine.

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